PolyCrystalline provides reliable solutions to optimise and control the crystallisation process of Active Pharmaceutical Ingredients for pharmaceutical companies, since 2005.

Our mission is to support our clients during drug development, helping them to reduce batch failure, avoiding costly crystallisation issues and overall offering greater confidence in drug quality during manufacturing. We can support you from early-phase drug discovery to kilogram supply.


We are a high performing cohesive team of trained chemists and analysts, with more than 10 years of experience in the development and optimization of APIs crystallization. We care about results and innovation based on sound science and the use of modern technologies.







order by visits date title

Equipment & Capabilities

PANalytical X'Pert3 Powder RIGAKU Miniflex 600 Malvern Morphologi G3 Malvern Mastersizer 3000  Mettler-Toledo DSC 1   Thermo Scientific Nicolet™ iS™50 (FT-IR/FT-RAMAN) Thermo Scientific Nicolet™ iS™10 TGA-IR Module Mettler-Toledo FBRM G400 Mettler-Toledo TGA/DSC1 Agilent ACQUITY UPLC-MS Mettler-Toledo EasyMax 102 Atlas Syrris Motic Microscope BA210 PLM Agilent 708-DS Di

Read all

Our History

In 2005 the company was born out of the Molecular Crystalline Engineering (MCE) group of research coordinated by Professor Dario Braga in the Department of Chemistry “G. Ciamician” of the University of Bologna. We are a high performing team that provides reliable solutions:1. STUDY YOUR TARGET API Structural Characterization, Water Content & Activity, Physical Characterization2. FIND & SELECT NOVEL FORMSPolymorph Screening, Solvate/Hydrate Identification, Salt/Co-Crystal Screening, Amorphous

Read all


Chemo Group Helsinn Biofer Rottapharm Chemi Lusochimica ACS Dobfar Angelini Fabbrica Italiana Sintetici Giuliani Pharma Bracco Novartis Chiesi Farmaceutici Dipharma Fresenius Kabi Menarini Cerbios Recordati Dompè Tonix Pharmaceuticals Rivopharm Infa Group Farchemia Italfarmaco Zambon Group Zach System

Read all

© Copyright Polycrystalline SpA - All rights reserved - VAT IT02600021204 / powered by DibiWeb