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9th Crystal Forms@BO Convention

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lunedì 2 maggio 2016


The investigation and optimization of crystal forms are at the forefront of industrial as well as fundamental research.

The event will bring together academic and industrial experts interested in sharing experience and discussing perspectives and new challenges regarding:

  • Recent advances in solid forms discovery
  • Synthesis and properties of crystal forms
  • Multicomponent crystal forms
  • Intellectual property issues

The convention is organized jointly, as in the past editions, by the group of Molecular Crystal Engineering of the Department of Chemistry of the University of Bologna and by PolyCrystalLine.


The convention will address not only issues at the frontier of the field, where “curiosity driven” and applied research interplay in a synergistic way, but also the practical implications in defining crystallization techniques and developing process control.


Please follow this link:


Sunday 4 June
Aula Magna Chemistry Department "G. Ciamician" – Via Selmi, 2

12:00 Registration
14:00 Welcome address
14:30 Susan M Reutzel-Edens, Senior Research Advisor, Small Molecule Design & Development at Eli Lilly and Company, “Exploring solid form landscapes: What to do when the best laid plans go awry”
15:00 Michael Zaworotko, Bernal Chair of Crystal Engineering & Science Foundation of Ireland Research Professor at University of Limerick, “Crystalline hydrates.”
15:30 Judith Aronhime, Director solid state characterization TAPI global R&D at Teva Pharmaceutical Industries Ltd., “Late-appearing polymorphs”
16:00 Jon Steed, Professor of Chemistry at Durham University, “Solid form control using supramolecular gels”
16:30 Coffee break
17:00 Amy Robertson, Team Manager, Right Particle Team, Chemical Development at AstraZeneca, “The use of crystal structures in pharmaceutical process understanding”
17:30 Juan J. Novoa, Dept. Quimica Fisica & IQTCUB, Fac. Quimica, Univ. Barcelona, “Understanding the mechanism and speed of polymorphic phase transitions: a case example in controlling bistability”
18:00 A. J. Cruz-Cabeza, Giulio I. Lampronti, University of Cambridge & University of Manchester, “Solvation and surface effects on polymorph stabilities at the nanoscale”
18:30 Gérard Coquerel, Simon Clevers & Morgane Sanselme, Université de Rouen, “Benefits of the -θ/-θ  X-ray powder diffraction geometry (In-situX®) in the monitoring of crystallization in solution”
19:00 Wine and cheese party

Monday 5 June
Sala Conferenze Hotel Europa - Via Cesare Boldrini, 11

9:00 Tom Leyssens, Professor physical chemistry at Université catholique de Louvain, “Amino acids in co-crystallization: complexity, utility and patent issues”
9:30 Ana Kwokal, Technology Lead / API Physical Characterisation at GSK, “Anhydrous to Hydrate and vice versa; why does it matter for pharmaceuticals?”
10:00 Nicholas Blagden, Professor in Pharmaceutics, Physical Pharmaceutics, Crystallisation and Crystal Engineering School Pharmacy University Lincoln UK “Crystallisation of multi component dipeptide complexes: The impact of synthesis”
10:30 Coffee break
11:00 Walkiria Schlindwein, Programme Leader (MSc in Pharmaceutical Quality by Design) Leicester School of Pharmacy Faculty of Health & Life Sciences, “Continuous pharmaceutical product development: A quality by design approach.”
11:30 Francesco Amadei, Senior Scientist, Early Pharmaceutics Unit, Head Analytics and Early Formulations Dept. Corporate Preclinical R&D at Chiesi Farmaceutici Spa, “Identification of crystalline forms suitable for inhalation in drug discovery.”
12:00 Alastair Florence, Director of the EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC), University of Strathclyde, “Continuous crystallisation: workflows and technologies for consistent crystals.”
12:30 Alfred Lee, Merck Research Laboratories at Merck Sharpe & Dohme Corp., "Solvates in Chemical & Pharmaceutical Development: A Blessing or a Nuisance”
13:00 Lunch
14:30 Marcus Neumann, Avant-garde Materials Simulation, “Organic crystal structure prediction - from fundamental research to industrial application”
15:00 Alessia Bacchi, Associate professor at University of Parma, “New solid forms of drugs and nutraceuticals by co-crystallization and crystalline sponge approaches”
15:30 Oertling Heiko, Senior Scientist Flavour Science bei Nestlé, “Ionic sugar salt cocrystals”
16:00 Coffee break & Posters
17:00 Luc Aerts, ‎Head Solid State Characterization and Development at UCB Pharma, “On hydrate forms and their relative stability vs. the anhydrous forms”
17:30 Ulrich Griesser, Professor Dr. at University of Innsbruck, Title to be provided.
18:00-19:30 POSTER SESSION

Tuesday 6 June
Sala Conferenze Hotel Europa - Via Cesare Boldrini, 11

9:00 Fabrizia Grepioni, Lucia Maini, Dario Braga Dept of Chemistry G. Ciamician University of Bologna, “Solid solutions and chirality: adding new elements to the co-crystals palette”
9:30 Franziska Emmerling, Scientist Federal Institute for Materials Research and Testing, “In situ investigations of mechanochemical syntheses: new insights in formation pathways”
10:00 Enrico Modena, Luca Covello, Polycrystalline, “Avoid micronization controlling PSD”
10:30 Susan Bourne, Centre for Supramolecular Chemistry Research, University of Cape Town South Africa “Supramolecular property modification as a tool to tackle the African disease burden”
11:00 Coffee break
11:30 Michael Lange, Physicochemical properties and solid-state selection, Site Operations-Analytics at Merck Group, “Case study of solid state selection in the pharmaceutical industry”
12:00 Teresa Duarte, Full Professor at Instituto Superior Técnico Lisbon, “Polymorphic control - ionic liquids as crystallization directing agents”
12:30 Neil George, Science and Technology Fellow at Syngenta Crop Protection, “Solid State Control In Agrochemical Processing and Formulation”
13:00 Philippe Ochsenbein, Researcher at Sanofi-Aventis Montpellier, France “Combining Several Methods to Solve Pharma API Crystal Structures”
13:30 Lunch
15:00 Joel Bernstein, Global Distinguished Professor of Chemistry at New York University Abu Dhabi and Shanghai, “Structural chemistry, fuzzy logic and the law.”
15:30 Ilaria Goss, Examiner Directorate at European Patent Office (EPO), Title to be provided.
16:00 Jill K. MacAlpine, Partner at Finnegan, Henderson, Farabow, Garrett & Dunner LLP, “U.S. patent protection of crystal forms”
16:30 Coffee break and Round Table discussion: The evolution of crystal form protection – Chairman Joel Bernstein
18:00 Dario Braga (University of Bologna) Concluding remarks and Poster Prize


OPENING DAY 4th June 2017

Department of Chemistry "Giacomo Ciamician"

University of Bologna

Via Selmi, 2

40126Bologna - Italy

CONVENTION 5-6th June 2017

Zanhotel EUROPA

Via Cesare Boldrini, 11

40121 Bologna - Italy

PARKING: Zanhotel Europa has a private car parking area.


DIRECTIONS to Department of chemistry "Giacomo Ciamician"

DIRECTIONS to Zanhotel Europa


The convention will be held at Zanhotel Europa, refer to for e-mail reservations.

Please remember to indicate that you are a participant in the convention, in order to get the reduced-rate hotel rooms.


  • Single (B&B): 75 € + City Tax (2.50 € / night)
  • Double (B&B): 84 € + City Tax (1.50 € / night per person)

*All prices include VAT

Alternatively, the following are also within walking distance of the venue:


There are several packages available. All packages include branding, promotion opportunities and the majority include complimentary tickets. Please contact Luca Covello (

GOLD - 1,500€*


  • Company Logo and profile in the event guide
  • Company Logo and hyperlink on the event website
  • Insertion of promotional material in the Conference Bag
  • Space in the exhibition hall of CF@BO 2017
  • Showcase presentation during the event (30 minutes)

SILVER - 1,000€*


  • Company Logo and profile in the event guide
  • Company Logo and hyperlink on the event website
  • Insertion of promotional material in the Conference Bag
  • Space in the exhibition hall of CF@BO 2017

BRONZE - 500€*


  • Company Logo and profile in the event guide
  • Company Logo and hyperlink on the event website
  • Insertion of promotional material in the Conference Bag

* VAT not included (where applicable)


Professor Dario Braga


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