Salt formation is one of the primary solid-state approaches used to modify the physical properties of APIs. However, a major limitation within this approach is that the API must possess a suitable (basic or acidic) ionisable site. In comparison, co-crystals offer a different pathway, where any API regardless of acidic, basic or ionisable groups, could potentially be co-crystallized.
How can we help you?
- Investigate the formation of salts when the API itself is not sufficiently soluble or stable, or is difficult to formulate or manufacture
- Possibility of discovering new patentable solid forms